I'm not absolutely sure Parallels has anything to do with it, but I do wonder. The problem: I have an HP8500, a Brother MFC8440, an Epson Stylus RX500, and a Canon MX320. Suddenly and inexplicably, several months after upgrading to Lion but within two or three weeks of installing Parallels, I find that I have no ability to scan using any of these devices. Image Caputre says no scanner or camera is connected and Preview simply does not find a scanning device. Three of the scanners are currently attached and appear as printers and will print. I have reset the printing system and re-installed the printers, even downloading the Lion drivers from the manufacturer, and nothing works. Think maybe Parallels might have killed my scanning capability? At one point I could still scan using XP via Parallels, but now the scanners don't work in XP either.