With all due respect, it does work in Intel OS X.
I downloaded version 5.3.2.10 from VersionTracker: http://www.versiontracker.com/dyn/moreinfo/macosx/21994 and successfully updated my 880 remote.
I'd suggest removing any older installations from your Applications folder and the Harmony kernel extension from /system/library/extensions before installing.
You need to go into the Harmony remote preferences and tell it to watch the same download folder as Safari (their instructions).
The Harmony remote is PowerPC but works perfectly in Rosetta in Intel OS X. You do not need Parallels to maintain your Harmony remote.
HTH,
Loyd
Last edited: Jun 22, 2006