you have a choice at home and in small shops...but in large companies (especially publicly traded, sarbanes-oxley compliant shops), the mandate is for antivirus to not only be installed, but daily definitions update and locked down settings. no choice in the matter at these large shops. in shops managed by saavy sysadmins, virtual systems like parallels are binded and controlled as tightly as physical pc's. shops that have behind-cutting-edge sysadmins, you can count on mandates covering these virtual computers as well as physical computers. two large shops even have "virtual computer" entries in active directory. 
i have four macs. one macbook pro, one 12" powerbook, one g4 tower and one g5 xserver....these all have clamxav installed and configured to scan desktop/email/downloads/expanding files - along with nightly scans of entire computer (quarantine folder in /Users/Shared). i have two pc's...one real pc (dell c400 laptop) and one bootcamp (partition on macbook pro)....these both have nav and are set up the same way as the macs...with the exception that active scanning is on (as per sox mandates at my client shops).
it's a tough choice...whether to have nav installed on a mac. despite the relative immunity to viruses/trojans/etc., i would never allow my mac computers to become party to infection of any pc computers at home or at a client shop. that being said, i use clamxav which is unintrusive and doesn't cause a noticeable performance hit (since it only scans as outlined above). however, i would never run any windows computer without norton antivirus installed and configured. i don't have a choice in that matter given my profession.
ps, in production environments, where i.t. has desktops locked down, proxy servers in place, domain filtering/blocking in place, and tight control over what can be downloaded/uploaded, AND where i.t. isn't bound by sox compliance...i could see not having any antivirus installed at the desktop (however, in shops that run this way, you can bet that your sysadmins are scanning everything that hits their servers). 
don
Last edited: Dec 10, 2006